1. 概述

在全球范围内，妇科恶性肿瘤对女性的生命健康带来严重威胁。根据国际癌症研究机构2020年发布的数据，全球每年新增约133万例妇科恶性肿瘤患者，死亡约54万例，疾病负担十分沉重。其中，宫颈癌、卵巢癌和子宫内膜癌是三大较为常见的妇科恶性肿瘤。

2024年，妇科肿瘤的诊治工作取得了显著的进展，尤其在免疫治疗、靶向治疗、抗体药物偶联物（ADC）治疗以及联合疗法等方面取得了重要突破。相关的基础研究与药物治疗的临床研究革新传统治疗并推动了诊疗模式的创新，特别是在卵巢癌、宫颈癌和子宫内膜癌的治疗中，多项高水平研究成果相继发表，有力地推动了临床诊疗实践的发展，显著改善了患者的预后和生存质量。卵巢恶性肿瘤作为恶性程度最高的妇科肿瘤，严重威胁女性的生命健康，传统的治疗方式始终无法满足临床上对于改善患者预后的需求，因而对于卵巢癌的研究始终是妇科肿瘤的重点。

本文总结并回顾了2024年妇科肿瘤相关临床研究的重大进展，以期更好地指导临床个体化精准治疗。

【主编】

吴小华   复旦大学附属肿瘤医院

【副主编】

朱 俊   复旦大学附属肿瘤医院

【编委】

温 灏   复旦大学附属肿瘤医院

郭勤浩   复旦大学附属肿瘤医院

冯 征   复旦大学附属肿瘤医院

陈小军   复旦大学附属肿瘤医院

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